US to Offer Uterus Transplants

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Should uterus transplants be publicly funded?

Since 2000, 11 human uterine transplantation procedures (UTx) have been performed across Europe and Asia. Five of these have, to date, resulted in pregnancy and four live births have now been recorded. The most significant obstacles to the availability of UTx are presently scientific and technical, relating to the safety and efficacy of the procedure itself. However, if and when such obstacles ...

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Uterus transplants and their ethical implications.

Early experiments in womb transplants have increased interest in the possibility of performing this procedure in women who have no womb, usually for congenital reasons. The present article describes past experiments and summarises the most relevant reference documents before indicating the key ethical implications involved in womb transplants.

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Progesterone inhibits rejection of xenogeneic transplants in the sheep uterus.

OBJECTIVES One of the proposed roles of progesterone is to prevent maternal immunological destruction of the allogeneic conceptus. Here, it was demonstrated that progesterone allows survival of a xenotransplant placed in the uterine lumen. METHODS Ovariectomized ewes, surgically prepared to have ligatures around each uterine horn, were given daily subcutaneous injections of 50 mg progesterone...

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Other women's wombs: uterus transplants and gestational surrogacy

The birth of a child after uterus transplant from a living donor in Sweden in October, 2013 has spurred reproductive and transplant physicians in Europe and North America to investigate whether uterus transplants, from living or cadaveric donors, will be a safe and effective therapy for women with uterine insufficiency. While progress with uterus transplant depends on medical factors, there are...

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Public funding, social change and uterus transplants: a response to commentaries

Our paper ‘Should the State Fund Uterus Transplants?’ was recently published as a feature article alongside commentaries by Alghrani, Balayla and Lotz. We would like to thank all three for their insightful and careful analyses and JME for providing us with the opportunity to publish in this format. The commentaries were generally favourable and we have little to add regarding the pieces by Algh...

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ژورنال

عنوان ژورنال: American Journal of Transplantation

سال: 2016

ISSN: 1600-6135

DOI: 10.1111/ajt.13718